News Pressroom

October 28, 2004

CDC Advisory Committee Votes to Include FluMist(R) in the Vaccines for Children Program for 2005-2006 Influenza Season

GAITHERSBURG, Md., Oct. 28 /PRNewswire-FirstCall/ -- MedImmune, Inc. (Nasdaq: MEDI) announced today that FluMist (Influenza Virus Vaccine Live, Intranasal) has been included in the federal government's Vaccines for Children (VFC) program as an alternative to the injectable flu vaccine beginning in the 2005-2006 influenza season. As a result of this vote by the U.S. Centers for Disease Control and Prevention's (CDC) Advisory Committee on Immunization Practices (ACIP), healthy children ages 5 to 18 years who meet the eligibility requirements of the VFC program may receive FluMist at no cost next season.

"The addition of FluMist to the VFC program is an important step in ensuring that more children have access to the benefits of newly recommended vaccines," said Caroline York, vice president, government affairs and reimbursement, at MedImmune. "We are pleased to join in the nationwide endeavor to help keep children and families healthy during the influenza season."

For the 2004-2005 influenza season, the CDC has encouraged the use of intranasally administered, live, attenuated influenza vaccine (FluMist), if available, for healthy, non-pregnant individuals ages 5 to 49 years, including healthcare workers (except those who care for severely immunocompromised patients in special care units) and individuals caring for children younger than six months.

About Vaccines for Children

In an effort to increase childhood immunization levels, the VFC program provides federally purchased vaccines to children who are enrolled in Medicaid, or who are uninsured, underinsured, American Indian or Alaskan Native. Many families in these groups cannot afford to pay for vaccines, which can lead to low immunization levels and disease outbreaks within communities.

"The VFC program is a vital source of vaccines for low-income children across the United States," said Stanley L. Block, Jr., M.D., pediatrician at Kentucky Pediatric Research. "We experienced last year how severe influenza can be among even healthy children. Offering FluMist through this program as an alternative flu vaccine option for future seasons could help prevent major influenza-related illness and even save the lives of children who otherwise wouldn't have the opportunity to get immunized. A nasal vaccine is most appealing for many of our children."

As the CDC reported on June 18, 2004, a total of 152 children younger than 18 years of age died in the U.S. from influenza and its complications during the 2003-2004 flu season. Seventy-one percent of these children had no high- risk medical conditions, as defined by the CDC. These statistics are a reminder that, despite the traditional emphasis on high-risk groups, healthy children are also vulnerable to influenza each year -- and deaths can occur.

About FluMist

FluMist is the first live, attenuated influenza vaccine indicated for active immunization for the prevention of disease caused by influenza A and B viruses in healthy children and adolescents, 5 to 17 years of age, and healthy adults, 18 to 49 years of age.

There are risks associated with all vaccines, including FluMist. FluMist does not protect 100-percent of individuals vaccinated, or may not protect against viral strains not represented in the vaccine. FluMist is contraindicated in persons with hypersensitivity to any component of the vaccine, including eggs; in children and adolescents receiving aspirin therapy or aspirin-containing therapy; in individuals with a history of Guillain-Barre syndrome; and in individuals with known or suspected immune deficiency. The safety and efficacy of FluMist have not been established in pregnant women or for patients with chronic underlying medical conditions, including asthma or reactive airways disease; the vaccine should not be administered to these patients. See Prescribing Information for indications and usage, dosage and administration and safety information.

About MedImmune

MedImmune strives to provide better medicines to patients, new medical options for physicians, rewarding careers to employees, and increased value to shareholders. Dedicated to advancing science and medicine to help people live better lives, the company is focused on the areas of pediatric infectious diseases, cancer and inflammatory diseases. With approximately 1,900 employees worldwide, MedImmune is headquartered in Maryland. For more information, visit the company's website at http://www.medimmune.com.

This announcement may contain, in addition to historical information, certain forward-looking statements that involve risks and uncertainties. Such statements reflect management's current views and are based on certain assumptions. Actual results could differ materially from those currently anticipated as a result of a number of factors, including risks and uncertainties discussed in the company's filings with the U.S. Securities and Exchange Commission. The company is developing several products for potential future marketing. There can be no assurance that such development efforts will succeed, that such products will receive required regulatory clearance or that, even if such regulatory clearance were received, such products would ultimately achieve commercial success.

SOURCE  MedImmune, Inc.
    -0-                             10/28/2004
    /CONTACT:  Media: Jamie Lacey, +1-301-398-4035; Investors: Peter Vozzo,
+1-301-398-4358, or John Filler, +1-301-398-4086, all of MedImmune, Inc./
    /Web site:  http://www.medimmune.com/
    (MEDI)

CO:  MedImmune, Inc.; U.S. Centers for Disease Control and Prevention; CDC
ST:  Maryland
IN:  HEA MTC
SU:  CHI

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3222 10/28/2004 10:17 EDT http://www.prnewswire.com