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February 22, 2005

MedImmune Announces New Senior Appointment and Five Executive Promotions

GAITHERSBURG, Md., Feb 22, 2005 /PRNewswire-FirstCall via COMTEX/ -- MedImmune, Inc. (Nasdaq: MEDI) announced today that Linda J. Peters has joined the management team as senior vice president, regulatory affairs. In addition, several existing members of the team have been promoted and assumed additional management responsibilities. Promotions include: Armando Anido, R.Ph., executive vice president, sales and marketing; Bernardus N.M. Machielse, Drs., senior vice president, operations; Edward T. Mathers, senior vice president, corporate development; Peter A. Kiener, D.Phil., senior vice president, research; and Charles F. Katzer, vice president, vaccine manufacturing.

"MedImmune continues to attract and develop world-class management talent," said David M. Mott, chief executive officer and president. "Linda Peters brings tremendous regulatory experience and outstanding general management skills to our regulatory affairs team. The promotions of Armando Anido, Ed Mathers, Peter Kiener and Chuck Katzer reflect their growth and increasing contributions to our business. The promotion of Ben Machielse reflects his outstanding contributions to our business and supports the organizational objective of creating a more efficient and collaborative operations team among the manufacturing, supply chain and quality organizations. We are fortunate to have each of these outstanding professionals on our leadership team."

New Senior Appointment

Linda J. Peters joins MedImmune as senior vice president, regulatory affairs where she will be responsible for defining and orchestrating the company's global regulatory strategy. Prior to joining the company, Ms. Peters was vice president of global regulatory affairs for the Bioscience and Renal Divisions of Baxter Healthcare. While at Baxter, she was responsible for implementing global regulatory strategies for biologics, vaccines, drugs, biosurgical products and devices, which included several new product approvals worldwide. Previously, Ms. Peters was director, regulatory affairs for Takeda Pharmaceuticals North America where she was responsible for the regulatory management of more than a dozen new compounds and marketed products. As the first regulatory affairs scientist at Takeda, she created a regulatory vision for the company and successfully established a department of more than 30 regulatory professionals in less than three years. Ms. Peters was also involved with the U.S. approval and launch of ACTOS (pioglitazone HCl), a drug for the treatment of Type II diabetes. In addition, she held positions of increasing responsibility at TAP Pharmaceuticals, which included regulatory approval for several new indications for PRECAVID (lansoprazole), an anti- ulcer drug. Ms. Peters earned her bachelor of science and master of science degrees in animal science from Southern Illinois University. She also holds a master of business administration degree from the J.L. Kellogg School of Management at Northwestern University. In her new role at MedImmune, Ms. Peters will report to James F. Young, Ph.D., president, research and development.

Executive Promotions

As executive vice president, sales and marketing, Armando Anido is responsible for overseeing the company's global commercial activities. He also plays an integral role in defining the strategic vision of the company. Anido joined MedImmune in 1999 as senior vice president, sales and marketing. Prior to joining MedImmune, Mr. Anido was vice president of CNS Marketing at Glaxo Wellcome, Inc. During his time with Glaxo Wellcome, Mr. Anido had profit and loss responsibility for a CNS business, managed the CNS marketing team, and was directly responsible for the launches of seven products/line extensions within 24 months. Mr. Anido also held various positions at Lederle Laboratories, culminating in his service as the vice president of anti- infectives marketing. Mr. Anido is a registered pharmacist, and holds a bachelor's degree in pharmacy and a master of business administration from West Virginia University.

Edward T. Mathers is MedImmune's senior vice president, corporate development, where he is responsible for the company's licensing and business development activities. He also works closely with our MedImmune Ventures team on the evaluation of investment opportunities. Prior to joining MedImmune in 2002, Mr. Mathers was vice president of marketing and corporate licensing and acquisitions at Inhale Therapeutic Systems. Previously, he enjoyed a successful 15-year career at Glaxo Wellcome, Inc., holding a number of increasingly responsible positions in sales and marketing. Mr. Mathers began his career as a researcher at Ortho Pharmaceuticals Corporation, a division of Johnson & Johnson. Mr. Mathers holds a bachelor's degree in chemistry from North Carolina State University.

As senior vice president, research, Dr. Peter Kiener oversees the company's global research activities. Prior to joining MedImmune in 2001, Dr. Kiener spent 18 years with Bristol-Myers Squibb's Pharmaceutical Research Division. Previously, Dr. Kiener spent several years in the academic setting as an assistant professor at the University of North Texas/Texas College of Osteopathic Medicine's Department of Anatomy; as a research associate at the Department of Biochemistry, University of Massachusetts (Amherst); and, as a postdoctoral research assistant, Medical Research Council, Sir William Dunn School of Pathology, University of Oxford. Dr. Kiener holds a bachelor of science degree with honors in chemistry from Lancaster University, Lancaster, the United Kingdom, and a doctorate of philosophy in biochemistry from the Oxford University, Sir William Dunn School of Pathology, Oxford, England.

Expanded Management Responsibilities in Operations

In January 2005, Drs. Bernardus N.M. Machielse, senior vice president, operations, assumed responsibility for all manufacturing and supply chain operations, in addition to his responsibility for MedImmune's quality operations. The expansion of Drs. Machielse's role reflects his significant contributions to MedImmune and particularly to its quality, manufacturing and operations functions since he joined the company in May 1999. During his tenure he has led the growth of the quality department from 80 to more than 250 people, including the incorporation of the quality-related activities from the U.S. Bioscience and Aviron acquisitions. Prior to joining MedImmune, Drs. Machielse was vice president, quality control and quality assurance, for Xoma Corporation. He also spent several years in various manufacturing and quality positions at Centocor BV of the Netherlands. Drs. Machielse holds a bachelor of science degree in medical biology and a master of science degree in biochemistry from the University of Utrecht, the Netherlands.

In January 2005, Charles F. Katzer, vice president, vaccine manufacturing assumed responsibility for the company's global vaccine manufacturing operations. Previously, Mr. Katzer was vice president and site director of manufacturing activities in Pennsylvania. Prior to joining MedImmune in 2000, Mr. Katzer served as vice president, operations for U.S. Bioscience, Inc. Earlier in his career, he was senior director, operations for Immunomedics and held numerous management positions for Rhone Poulenc Rorer, McGaw Laboratories, Baxter Travenol Laboratories and Biological Specialties. Mr. Katzer received his bachelor's degree in zoology from the University of Wisconsin where he also served as a research assistant in parasitology.

About MedImmune, Inc.

MedImmune strives to provide better medicines to patients, new medical options for physicians, rewarding careers to employees, and increased value to shareholders. Dedicated to advancing science and medicine to help people live better lives, the company is focused on the areas of infectious diseases, cancer and inflammatory diseases. With approximately 2,000 employees worldwide, MedImmune is headquartered in Maryland. For more information, visit the company's website at http://www.medimmune.com.

This announcement may contain, in addition to historical information, certain forward-looking statements that involve risks and uncertainties. Such statements reflect management's current views and are based on certain assumptions. Actual results could differ materially from those currently anticipated as a result of a number of factors, including risks and uncertainties discussed in MedImmune's filings with the U.S. Securities and Exchange Commission. The company is developing several products for potential future marketing. There can be no assurance that such development efforts will succeed, that such products will receive required regulatory clearance or that, even if such regulatory clearance were received, such products would ultimately achieve commercial success.

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